My husband has always suffered quite badly with headaches and was on beta blockers for some years in an attempt to control the problem. Since weaning himself off these a few years ago his headaches have increased in both frequency and severity. He has undergone a number of tests and been prescribed various medications over the last 6 months. Today he has been prescribed Pizotifen. I have just Googled this drug (I know, I know!) and feel quite alarmed by the reported side effects. A number of users of this drug have reported large and fast weight gains, amongst other side effects, including drowsiness and mood changes. However, the majority of posters on the health forums do say that the Pizotifen is helping their headaches. Does anyone here have personal experience, good or bad, of this medication?