My ex had ME for about 6 years after a bout of glandular fever. She worked too hard and it took a long time to recover. She has recovered - interestingly after she became pregnant! Not sure if that's recommended. She was told so much - cognitive behaviour, graded exercise, it's all in your head. She did pace herself and made herself do things - but also got payback later. Another friend of mine had severe ME for 10 years. She was almost bedbound. She did some therapy and is a different person. She runs her own business and leads a full and active social life. It's amazing to see how she has changed.