Hubcap Biology GCSE C and above is fine, as is Physics, Chemistry and Combined Sciences, most Universities won't accept Human Biology. The old CSE is fine as well, but only if it Grade 1. Universities can also specify what type of Science qualification they want as well, checked into this last year before I started my Science GCSE. Some do accept equivalency tests but they are not always transferrable so may only apply for that specific university. The university I want to apply for has stopped equivalency testing so it is worth ringing round to check. Science wasn't my strong point either, but if you go for the foundation paper and aim for the C grade it isn't too bad! The GCSE I'm doing is multiple choice, you sit the exams at different times of the year and you get chances to retake them if you don't pass them first time around. I did however find it hard to find a course because I was an adult, there were loads for English and Maths but hardly any for Science, the majority were for school leavers. I looked into distance learning and a private tutor as well but decided to go to night school because I wanted the ongoing tutor support. I've juggled it and I've found the Science more difficult than my degree, probably because I have to do the Science and I want to do the degree!! I'd advise you to look into all your options and make a few phonecalls. Good luck!